Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703450 | 0.83 | GAA (0.43) | GLP1RATMHIF1ALMNASMN1; SMN2 | |
| SCHEMBL9703948 | 0.81 | ATM (0.37) | GLP1RATMHIF1ALMNASMN1; SMN2 | |
| SCHEMBL9705817 | 0.76 | HIF1A (0.31) | ATMHIF1AGAANPC1RAB9A | |
| SCHEMBL9704991 | 0.75 | GRIN2D (0.45) | GLP1RLMNASMN1; SMN2NPSR1GRIN2D | |
| SCHEMBL9703518 | 0.67 | GAA (0.47) | GLP1RATMLMNAGAATSHR | |
| SCHEMBL9703410 | 0.65 | GRIN2D (0.68) | LMNASMN1; SMN2GAATSHRMEN1 | |
| SCHEMBL31186096 | 0.63 | SMN1; SMN2 (0.42) | HIF1ALMNASMN1; SMN2NPSR1GAA | |
| SCHEMBL9703688 | 0.63 | NPC1 (0.45) | ATMLMNASMN1; SMN2NPSR1MEN1 | |
| SCHEMBL9813328 | 0.61 | CHRNB2 (0.46) | LMNASMN1; SMN2NPSR1CHRNB2CHRNB4 | |
| SCHEMBL10353913 | 0.60 | GAA (0.54) | PGK1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |