Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703450 | 0.89 | GAA (0.43) | ATMGAATSHRGLP1RMEN1 | |
| SCHEMBL9705817 | 0.81 | HIF1A (0.31) | ATMGAAHIF1ANPC1RAB9A | |
| SCHEMBL9704210 | 0.81 | PGK1 (0.36) | ATMGAATSHRGLP1RMEN1 | |
| SCHEMBL9703955 | 0.76 | HRH4 (0.43) | GAATSHRGLP1RLMNAGRIN2D | |
| SCHEMBL9703518 | 0.71 | GAA (0.47) | ATMGAATSHRGLP1RHTR2A | |
| SCHEMBL9703856 | 0.63 | GRIN2D (0.49) | GLP1RMEN1KMT2ALMNAGRIN2D | |
| SCHEMBL31186096 | 0.62 | SMN1; SMN2 (0.42) | GAATSHRHIF1ALMNANPC1 | |
| SCHEMBL5821296 | 0.61 | CA12 (0.42) | GAATSHRMEN1KMT2ALMNA | |
| SCHEMBL9703926 | 0.60 | GRIN2D (0.74) | GAATSHRMEN1KMT2ALMNA | |
| SCHEMBL3614700 | 0.59 | ALDH1A1 (0.38) | TSHRCCNA2CDK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |