Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.63 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.63 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.63 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.63 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.63 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.63 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.63 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.63 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.63 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.63 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.63 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.63 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.63 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.63 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | GLP1R | P43220 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6376356 | 0.90 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11258206 | 0.90 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11369648 | 0.90 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6705309 | 0.86 | ALDH1A1 (0.46) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6603120 | 0.86 | GLP1R (0.50) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11363308 | 0.85 | GRIN2D (0.62) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11256884 | 0.85 | GRIN2D (0.68) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL9704059 | 0.84 | ADORA3 (0.55) | GLP1RSIRT2SIRT1SIRT3HRH4 | |
| SCHEMBL30623229 | 0.84 | ADORA3 (0.55) | GLP1RSIRT2SIRT1SIRT3HRH4 | |
| SCHEMBL6377225 | 0.84 | SIRT2 (0.56) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | claimed |
| EP-0020836-A1 | Antiviral combinations | ELI LILLY AND COMPANY (US) | 1981-01-07 | — | — | EP | claimed |
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |
| US-4355030-A | Antiviral combinations | ELI LILLY AND COMPANY (US) | 1982-10-19 | — | — | US | disclosed |
| US-4289773-A | ETHYL 6,7-DIBROMO-3,4-DIHYDRO-3-OXOQUINOXALINE CARBOXYLATE AND A HINDERED AMINE | ELI LILLY AND COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0029658-A1 | Salts of dihalo-2-quinoxaline carboxylic acids, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4271162-A | ETHYL 6,7-DICHLORO-3,4-DIHYDRO-3-ONOQUINOXALINE CARBOXYLATE AND 1-AMINOADAMANTANE | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4264600-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-04-28 | — | — | US | disclosed |
| US-4252954-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| EP-0020836-A1 | Antiviral combinations | ELI LILLY AND COMPANY (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4210647-A | INFLUENZA VIRUS, ETHYL 6,7-DIBROMO-3,4-DIHYDRO-3-OXO-2-QUINOXALINECARBOXYLATE, 1-AMINOADAMANTANE | ELI LILLY AND COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| EP-0010426-A1 | Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof | ELI LILLY AND COMPANY (US) | 1980-04-30 | — | — | EP | disclosed |