Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 3/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.51 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.51 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GLP1R | P43220 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703575 | 0.90 | GRIN2D (0.63) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11258206 | 0.85 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL11369648 | 0.83 | GRIN2D (0.51) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6602046 | 0.82 | KDM4E (0.43) | ADORA3 | |
| SCHEMBL6705309 | 0.82 | ALDH1A1 (0.46) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL6603120 | 0.81 | GLP1R (0.50) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL30623229 | 0.80 | ADORA3 (0.55) | GLP1RADORA3SIRT2SIRT1SIRT3 | |
| SCHEMBL6377225 | 0.80 | SIRT2 (0.56) | ADORA3SIRT2SIRT1SIRT3 | |
| SCHEMBL9704059 | 0.80 | ADORA3 (0.55) | GLP1RADORA3SIRT2SIRT1SIRT3 | |
| SCHEMBL11349805 | 0.80 | LMNA (0.43) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156047-B1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN SEIYAKU KK (JP) | 2005-08-31 | — | — | EP | disclosed |
| US-6632813-B1 | 6-subtituted-7-heteroquinoxalinecarboxylic acid derivatives and addition salts thereof and processes for the preparation of both | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1156047-A1 | 6-SUBSTITUTED-7- HETEROQUINOXALINE CARBOXYLIC ACID DERIVATIVES AND ADDITION SALTS THEREOF AND PROCESSES FOR THE PREPARATION OF BOTH | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | disclosed |