SCHEMBL9703627

SCHEMBL9703627

CO[Si](CCCNc1ccccc1NCCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.49
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.41
HTR1A P08908 6/20 0.40
ADRA1D P25100 6/20 0.40
ADRA1A P35348 6/20 0.40
ADRA1B P35368 6/20 0.40
KDM4E B2RXH2 2/20 0.38
GBA1 P04062 1/20 0.38
GLA P06280 1/20 0.38
NCF1 P14598 1/20 0.36
QPCT Q16769 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TLR8 Q9NR97 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6449056 0.90 MAPT (0.58) CHRM2MAPTHTTHTR1AADRA1D
SCHEMBL14682410 0.88 L3MBTL1 (0.49) CHRM2ALDH1A1GAAHPGD
SCHEMBL8029183 0.88 CHRM2 (0.43) CHRM2MAPTHTTHTR1AADRA1D
SCHEMBL14682415 0.88 CHRM2 (0.43) CHRM2MAPTHTTHTR1AADRA1D
SCHEMBL16798806 0.85 ALDH1A1 (0.56) MAPTHTR1AADRA1DADRA1AADRA1B
SCHEMBL961488 0.84 CHRM2 (0.40) CHRM2MAPTHTTHTR1AADRA1D
SCHEMBL6682395 0.83 MAPT (0.42) CHRM2MAPTHTTHTR1AADRA1D
SCHEMBL41158 0.83 MAPT (0.57) CHRM2MAPTALDH1A1GAA
SCHEMBL28828211 0.83 MAPT (0.57) CHRM2MAPTALDH1A1GAA
SCHEMBL9516492 0.81 CHRM2 (0.39) CHRM2MAPTHTTHTR1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5149839-A Improved impregnation, solvent resistance, heat resistance and low water absoprtion properties NITTO BOSEKI CO., LTD. (JP) 1992-09-22 US disclosed
US-5069971-A With epoxy resins, printed circuits, diaminoalklyalkoxysilane NITTO BOSEKI CO., LTD. (JP) 1991-12-03 US disclosed