Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703686 | 0.90 | HPGD (0.49) | HPGDHTTL3MBTL1TP53RAB9A | |
| SCHEMBL7106203 | 0.82 | FAAH (0.53) | L3MBTL1TP53KDM4EALDH1A1MAPT | |
| SCHEMBL10454736 | 0.74 | TP53 (0.43) | HPGDHTTL3MBTL1TP53RAB9A | |
| SCHEMBL880382 | 0.74 | HPGD (0.73) | HPGDHTTL3MBTL1RAB9AMEN1 | |
| SCHEMBL16589495 | 0.72 | HPGD (0.67) | HPGDHTTL3MBTL1TP53RAB9A | |
| SCHEMBL30824255 | 0.72 | HPGD (0.67) | HPGDHTTL3MBTL1RAB9AMEN1 | |
| SCHEMBL5322245 | 0.72 | HPGD (0.61) | HPGDHTTTP53RAB9AMEN1 | |
| SCHEMBL7591483 | 0.71 | KDM4E (0.70) | HTTRAB9AMEN1NPC1KMT2A | |
| SCHEMBL28449520 | 0.70 | KDM4E (0.64) | HPGDHTTL3MBTL1TP53RAB9A | |
| SCHEMBL17817603 | 0.70 | HPGD (1.00) | HPGDHTTL3MBTL1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |