SCHEMBL9703672

SCHEMBL9703672

O=C(O)c1nc2cc(F)ccc2[nH]c1=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
GRIN2D O15399 1/20 0.59
GRIN3B O60391 1/20 0.59
GRIK1 P39086 1/20 0.59
GRIA1 P42261 1/20 0.59
GRIA2 P42262 1/20 0.59
GRIA3 P42263 1/20 0.59
GRIA4 P48058 1/20 0.59
GRIN1 Q05586 1/20 0.59
GRIN2A Q12879 1/20 0.59
GRIK2 Q13002 1/20 0.59
GRIK3 Q13003 1/20 0.59
GRIN2B Q13224 1/20 0.59
GRIN2C Q14957 1/20 0.59
GRIK4 Q16099 1/20 0.59
GRIK5 Q16478 1/20 0.59
GRIN3A Q8TCU5 1/20 0.59
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.47
DAO P14920 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704358 0.81 GRIN2D (0.68) LMNAGRIN2DGRIN3BGRIK1GRIA1
SCHEMBL11353502 0.81 GRIN2D (0.67) LMNAGRIN2DGRIN3BGRIK1GRIA1
SCHEMBL9704290 0.81 GRIN2D (0.55) LMNAGRIN2DGRIN3BGRIK1GRIA1
SCHEMBL6604320 0.79 TSHR (0.48) LMNAKDM4EHPGDALDH1A1TSHR
SCHEMBL2243699 0.79 PIN1 (0.53) LMNAKDM4EHPGDDAOPDPK1
SCHEMBL9703415 0.78 GRIN2D (0.67) LMNAGRIN2DGRIN3BGRIK1GRIA1
SCHEMBL9704060 0.77 GRIN2D (0.71) GRIN2DGRIN3BGRIK1GRIA1GRIA2
SCHEMBL880382 0.77 HPGD (0.73) LMNAGRIN2DGRIN3BGRIK1GRIA1
SCHEMBL9704143 0.77 MEN1 (0.58) LMNAGRIN2DGRIN3BGRIK1GRIA1
SCHEMBL6602314 0.76 GRIN2D (0.60) LMNAGRIN2DGRIN3BGRIK1GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992011245-A1 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY WARNER-LAMBERT COMPANY (US) 1992-07-09 WO disclosed