Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.55 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705656 | 0.81 | KDM4E (0.50) | HPGDMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2361454 | 0.81 | PIN1 (0.49) | LMNAHPGDHTTPIN1EGLN1 | |
| SCHEMBL9703672 | 0.81 | LMNA (0.59) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL9703455 | 0.79 | GRIN2D (0.67) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL9704358 | 0.78 | GRIN2D (0.68) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL6602090 | 0.75 | GRIA1 (0.56) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL6606848 | 0.75 | GRIA1 (0.56) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL2360781 | 0.75 | HRH4 (0.51) | LMNAHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5769256 | 0.74 | PARP1 (0.41) | PARP1MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL3372786 | 0.74 | MAOB (0.46) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |