Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 18/20 | 0.74 |
| ▸ | PRMT6 | Q96LA8 | 18/20 | 0.74 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9556188 | 0.99 | CARM1 (0.72) | CARM1PRMT6PRMT8HRH3TMEM97 | |
| SCHEMBL5102255 | 0.85 | CARM1 (0.65) | CARM1PRMT6PRMT8HRH3TMEM97 | |
| SCHEMBL12342532 | 0.83 | CARM1 (0.74) | CARM1PRMT6PRMT8HRH3TMEM97 | |
| Hydrochloric Acid SCHEMBL2334669 | 0.82 | CARM1 (0.72) | CARM1PRMT6PRMT8HRH3TMEM97 | |
| SCHEMBL19838617 | 0.81 | HTR7 (0.51) | CARM1PRMT6PRMT8HRH3HTR2A | |
| Hydrochloric Acid SCHEMBL10964879 | 0.79 | HRH3 (0.66) | CARM1PRMT6HRH3HTR2AHTR7 | |
| SCHEMBL9556062 | 0.78 | HTR2A (0.49) | CARM1PRMT6HRH3HTR2AHTR7 | |
| SCHEMBL19852276 | 0.78 | DRD2 (0.52) | CARM1PRMT6HRH3 | |
| SCHEMBL10274500 | 0.78 | HRH3 (0.63) | HRH3HTR2AHTR7 | |
| SCHEMBL10423401 | 0.78 | CARM1 (0.58) | CARM1PRMT6PRMT8HRH3TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0480794-A1 | 2-Aminopyrimidine-4-carboxamide derivatives, their preparation and therapeutic use | SYNTHELABO (FR) | 1992-04-15 | — | — | EP | disclosed |