Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6705309 | 0.85 | ALDH1A1 (0.46) | KMT2AKDM4EMAPTMEN1SMN1; SMN2 | |
| SCHEMBL880365 | 0.85 | ALDH1A1 (0.62) | KMT2AKDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL9704461 | 0.83 | LMNA (0.43) | KDM4EMAPTLMNAALDH1A1HPGD | |
| SCHEMBL9705717 | 0.83 | SIRT2 (0.44) | KDM4EMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6375213 | 0.83 | ALDH1A1 (0.53) | KMT2AKDM4EMAPTMEN1SMN1; SMN2 | |
| SCHEMBL11349805 | 0.83 | LMNA (0.43) | KMT2AKDM4EMAPTLMNAALDH1A1 | |
| Butane SCHEMBL7847687 | 0.83 | ALDH1A1 (0.60) | KMT2AKDM4EMAPTSMN1; SMN2LMNA | |
| SCHEMBL9703575 | 0.83 | GRIN2D (0.63) | LMNAGAA | |
| SCHEMBL6377630 | 0.83 | ALDH1A1 (0.51) | KMT2AKDM4EMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3995236 | 0.82 | ALDH1A1 (0.53) | KDM4EMAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |