Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711264 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1LMNANPSR1 | |
| SCHEMBL9704151 | 0.79 | HTR6 (0.55) | HTR6ALDH1A1TDP1KMT2ANFE2L2 | |
| SCHEMBL13370774 | 0.78 | HTR6 (0.58) | HTR6KMT2ANFE2L2KCNH2CA12 | |
| SCHEMBL4247206 | 0.78 | HTR6 (0.58) | HTR6KMT2ANFE2L2KCNH2CA12 | |
| SCHEMBL9652718 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TDP1KMT2ANFE2L2MEN1 | |
| SCHEMBL7525497 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1LMNAAMY1ANPSR1KMT2A | |
| SCHEMBL9350111 | 0.76 | MEN1 (0.48) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL9711172 | 0.75 | CA1 (0.50) | HTR6ALDH1A1KMT2ANFE2L2MEN1 | |
| SCHEMBL9740686 | 0.74 | HSD11B1 (0.41) | ALDH1A1L3MBTL1MAPTKMT2ANFE2L2 | |
| SCHEMBL9740023 | 0.74 | PLCG1 (0.60) | TDP1L3MBTL1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |