Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | PRKX | P51817 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.52 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602465 | 0.93 | CHEK1 (0.53) | GAACHEK1DAPK3PRKD3MET | |
| SCHEMBL6605386 | 0.91 | CHEK1 (0.49) | GAACHEK1DAPK3PRKD3MET | |
| SCHEMBL6608335 | 0.91 | CHEK1 (0.49) | GAACHEK1DAPK3PRKD3MET | |
| SCHEMBL6377308 | 0.90 | CHEK1 (0.46) | GAACHEK1DAPK3PRKD3MET | |
| SCHEMBL6607094 | 0.88 | CHEK1 (0.47) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL9703937 | 0.83 | KCNJ1 (0.54) | ALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL11371536 | 0.83 | MAPT (0.48) | GAACHEK1DAPK3PRKD3MET | |
| SCHEMBL6705309 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBHPGDSMN1; SMN2 | |
| SCHEMBL11450932 | 0.81 | CHEK1 (0.48) | CHEK1DAPK3PRKD3METPDGFRA | |
| SCHEMBL11349805 | 0.80 | LMNA (0.43) | GAAALDH1A1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |