Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703323 | 0.86 | CDK4 (0.47) | CDK4CCND1AMY1ACCNA2CDK2 | |
| SCHEMBL10745609 | 0.83 | AMY1A (0.58) | AMY1APDE2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9703617 | 0.82 | AMY1A (0.42) | AMY1APDE3BPDE3APDE5ATP53 | |
| SCHEMBL10764848 | 0.81 | PDE2A (0.47) | CDK4CCND1AMY1APDE2AKDM4E | |
| SCHEMBL9704539 | 0.80 | AMY1A (0.40) | CDK4CCND1AMY1ACCNA2CDK2 | |
| SCHEMBL10741648 | 0.80 | PDE2A (0.44) | CDK4CCND1AMY1APDE2AKDM4E | |
| SCHEMBL10744183 | 0.80 | PDE2A (0.51) | CDK4CCND1AMY1APDE2AKDM4E | |
| SCHEMBL10970632 | 0.79 | PDE2A (0.45) | CDK4CCND1AMY1APDE2AKDM4E | |
| SCHEMBL9678840 | 0.78 | KDM4E (0.43) | CDK4CCND1AMY1APDE2AKDM4E | |
| SCHEMBL10743168 | 0.78 | AMY1A (0.54) | CDK4CCND1AMY1APDE2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116843-A | Anticoagulants, hypotensive agents and cardiovascular disorder | BOEHRINGER MANNHEIM GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0275888-A2 | Tricyclic benzimidazoles, process for their preparation and use as medicaments | Roche Diagnostics GmbH (DE) | 1988-07-27 | — | — | EP | disclosed |