Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408207 | 0.79 | LDHA (0.38) | LDHASRRTP53CYP2D6CYP2C19 | |
| SCHEMBL2517722 | 0.79 | LDHA (0.38) | LDHASRRTP53CYP2D6CYP2C19 | |
| SCHEMBL8212718 | 0.76 | LMNA (0.47) | TP53SLC22A6LMNAGABRPGABRD | |
| Malonic Acid SCHEMBL30288562 | 0.76 | LDHA (0.64) | LDHASRRTP53SLC22A6CYP2D6 | |
| SCHEMBL19044324 | 0.74 | CYP1A2 (0.58) | CYP2D6CYP2C19GABRPGABRDGABRA1 | |
| Malonic Acid SCHEMBL5996614 | 0.71 | TP53 (0.69) | LDHASRRTP53SLC22A6CYP2D6 | |
| Malonic Acid SCHEMBL5874737 | 0.71 | LDHA (0.56) | LDHASRRTP53SLC22A6CYP2D6 | |
| Malonic Acid SCHEMBL10430517 | 0.71 | LDHA (0.56) | LDHASRRTP53SLC22A6CYP2D6 | |
| Malonic Acid SCHEMBL22499636 | 0.69 | LDHA (0.64) | LDHASRRTP53CYP2D6CYP2C19 | |
| Malonic Acid SCHEMBL27964676 | 0.69 | LDHA (0.64) | LDHASRRTP53CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192210-B1 | CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |