SCHEMBL9704730

SCHEMBL9704730

FC(F)(F)c1cc(Cl)c(-n2nc(CCl)nc2Cl)c(Cl)c1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRB3 P28472 19/20 0.47
GABRA2 P47869 13/20 0.47
GABRB2 P47870 13/20 0.47
GABRP O00591 7/20 0.45
GABRD O14764 7/20 0.45
GABRA1 P14867 7/20 0.45
GABRB1 P18505 7/20 0.45
GABRG2 P18507 7/20 0.45
GABRA5 P31644 7/20 0.45
GABRA3 P34903 7/20 0.45
GABRA4 P48169 7/20 0.45
GABRE P78334 7/20 0.45
GABRA6 Q16445 7/20 0.45
GABRG1 Q8N1C3 7/20 0.45
GABRG3 Q99928 7/20 0.45
GABRQ Q9UN88 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9703921 0.75 GABRB3 (0.44) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6976717 0.73 GABRB3 (0.51) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL9703827 0.71 GABRB3 (0.44) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10698854 0.69 GABRB3 (0.50) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL10778695 0.69 GABRB3 (0.50) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL6168749 0.68 GABRB3 (0.68) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL14996611 0.68 GABRB3 (0.52) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL27772986 0.68 GABRB3 (0.49) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL7711657 0.67 GABRB3 (0.67) GABRB3GABRA2GABRB2GABRPGABRD
SCHEMBL9704497 0.67 GABRB3 (0.46) GABRB3GABRA2GABRB2GABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013451-A1 IMIDAZOLE PESTICIDES SCHERING AGROCHEMICALS LIMITED (GB) 1992-08-20 WO disclosed