Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 19/20 | 0.68 |
| ▸ | GABRA2 | P47869 | 17/20 | 0.68 |
| ▸ | GABRB2 | P47870 | 17/20 | 0.68 |
| ▸ | GABRP | O00591 | 15/20 | 0.68 |
| ▸ | GABRD | O14764 | 15/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 15/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 15/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 15/20 | 0.68 |
| ▸ | GABRA5 | P31644 | 15/20 | 0.68 |
| ▸ | GABRA3 | P34903 | 15/20 | 0.68 |
| ▸ | GABRA4 | P48169 | 15/20 | 0.68 |
| ▸ | GABRE | P78334 | 15/20 | 0.68 |
| ▸ | GABRA6 | Q16445 | 15/20 | 0.68 |
| ▸ | GABRG1 | Q8N1C3 | 15/20 | 0.68 |
| ▸ | GABRG3 | Q99928 | 15/20 | 0.68 |
| ▸ | GABRQ | Q9UN88 | 15/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7711657 | 0.84 | GABRB3 (0.67) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6976717 | 0.84 | GABRB3 (0.51) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7713221 | 0.83 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6962955 | 0.83 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7707146 | 0.83 | GABRB3 (0.65) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10562514 | 0.82 | GABRA2 (0.64) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL5826687 | 0.82 | KDR (0.54) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL6054602 | 0.81 | GABRB3 (0.63) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL7814766 | 0.80 | GAA (0.52) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL239495 | 0.79 | GABRB3 (0.60) | GABRB3GABRA2GABRB2GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7070077-A | — | — | None | — | — | JP | disclosed |
| EP-0659745-B1 | Substituted 1-aryl pyrazoles | BAYER CROPSCIENCE AG (DE) | 2005-07-27 | — | — | EP | disclosed |
| CN-1106386-C | Parasiticidal pyrazoles | PFIZER LTD (US) | 2003-04-23 | — | — | CN | disclosed |
| EP-0946515-B1 | PARASITICIDAL PYRAZOLES | PFIZER LTD (GB) | 2003-03-05 | — | — | EP | disclosed |
| US-6372774-B1 | THESE COMPOUNDS POSSESS ARTHROPODICIDAL, PLANT NEMATOCIDAL, ANTHELMINTIC AND ANTI-PROTOZOAL PROPERTIES | RHONE-POULENC AGRICULTURE LTD. (GB) | 2002-04-16 | — | — | US | disclosed |
| US-RE37495-E1 | Substituted 1-arylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | disclosed |
| EP-0871617-B1 | PARASITICIDAL COMPOUNDS | PFIZER (US) | 2001-11-14 | — | — | EP | disclosed |
| US-6268509-B1 | PESTICIDES | PFIZER INC | 2001-07-31 | — | — | US | disclosed |
| US-6255333-B1 | HUMANS OR ANIMALS | PFIZER INC. | 2001-07-03 | — | — | US | disclosed |
| CN-1061037-C | Substituted 1-arylpyrazoles | BAYER AG (DE) | 2001-01-24 | — | — | CN | disclosed |
| US-4908377-A | Pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| US-4810720-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-03-07 | — | — | US | disclosed |
| US-4804675-A | 1-aryl-4-alkylthiopyrazol-5-amine derivatives, composition containing them, and method of using them to combat insects, arachnids, and nematodes | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| EP-0295482-A1 | Substituted 5-ethylamino-1-arylpyrazoles | BAYER AG (DE) | 1988-12-21 | — | — | EP | disclosed |
| EP-0249033-A1 | 5-Oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0234119-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-02 | — | — | EP | disclosed |
| EP-0231510-A2 | 1-Aryl pyrazoles | BAYER AG (DE) | 1987-08-12 | — | — | EP | disclosed |
| CN-86108643-A | Insecticidal method using N-phenylpyrazoles | — | 1987-07-29 | — | — | CN | disclosed |
| WO-1987003781-A1 | PESTICIDAL METHOD USING N-PHENYLPYRAZOLES | MAY & BAKER LIMITED (GB) | 1987-07-02 | — | — | WO | disclosed |
| EP-0201852-A2 | Agent against noxious plants based on pyrazol derivatives | BAYER AG (DE) | 1986-11-20 | — | — | EP | disclosed |