SCHEMBL9704827

SCHEMBL9704827

CCCc1nc2cc(N3C(=O)[C@H]4CCCC[C@H]4C3=O)c(C)nc2n1Cc1ccc(-c2ccccc2OC(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9704685 0.95 AGTR1 (0.47)
SCHEMBL9704813 0.91 PPARG (0.57) PPARG
SCHEMBL9704731 0.91 PPARG (0.43) PPARG
SCHEMBL9705915 0.89 PPARG (0.46) PPARG
SCHEMBL9705892 0.86 AGTR1 (0.44)
SCHEMBL9704668 0.86 AGTR1 (0.58) PPARG
SCHEMBL9703953 0.84 AGTR2 (0.49)
SCHEMBL9704627 0.84 PPARG (0.43) PPARG
SCHEMBL9704714 0.83 AGTR2 (0.48)
SCHEMBL9704746 0.83 AGTR1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0470543-A1 Heterocyclic imidazoles, remedies containing them and processes for their preparation Dr. Karl Thomae GmbH (DE) 1992-02-12 EP disclosed