Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | CDC25B | P30305 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087823 | 0.84 | HRH3 (0.50) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL29684111 | 0.82 | HRH3 (0.49) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL2940750 | 0.82 | HRH3 (0.49) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL38661680 | 0.81 | HRH3 (0.53) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL92726 | 0.81 | HRH3 (0.53) | APAF1CDC25BCASP3SENP8SENP7 | |
| Hydrochloric Acid SCHEMBL3714613 | 0.81 | HRH3 (0.47) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL7548161 | 0.79 | APAF1 (0.41) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL21047717 | 0.78 | APAF1 (0.47) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL3729545 | 0.78 | APAF1 (0.61) | APAF1CDC25BCASP3SENP8SENP7 | |
| SCHEMBL19051444 | 0.78 | APAF1 (1.00) | APAF1CDC25BCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041311-B | Fluorescent probe molecule ML-FP and preparation method and application thereof | 东南大学 | 2021-03-19 | — | — | CN | claimed |
| EP-0230179-B1 | 4-MORPHOLINYL 1H-INDOLE DERIVATIVES, THEIR SALTS, PROCESS AND INTERMEDIATES OF PREPARATION, USE AS THERAPEUTIC AGENTS, COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-09-30 | — | — | EP | disclosed |