Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940750 | 1.00 | HRH3 (0.49) | HRH3BCHEACHEAPAF1CDC25B | |
| Hydrochloric Acid SCHEMBL3714613 | 0.98 | HRH3 (0.47) | HRH3BCHEACHEAPAF1CDC25B | |
| SCHEMBL8087823 | 0.98 | HRH3 (0.50) | HRH3BCHEACHEAPAF1CDC25B | |
| Pyrrole SCHEMBL28092910 | 0.92 | HRH3 (0.50) | HRH3BCHEACHEAPAF1CDC25B | |
| Urea SCHEMBL28780664 | 0.91 | PLAU (0.48) | HRH3BCHEACHEAPAF1CDC25B | |
| Pyrimidine SCHEMBL28765153 | 0.89 | BCHE (0.44) | HRH3BCHEACHEAPAF1CDC25B | |
| SCHEMBL38661680 | 0.84 | HRH3 (0.53) | HRH3APAF1CDC25BCASP3SENP8 | |
| SCHEMBL92726 | 0.84 | HRH3 (0.53) | HRH3APAF1CDC25BCASP3SENP8 | |
| SCHEMBL7548161 | 0.82 | APAF1 (0.41) | HRH3BCHEACHEAPAF1CDC25B | |
| SCHEMBL9704853 | 0.82 | APAF1 (0.63) | BCHEACHEAPAF1CDC25BCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4703356-A1 | SALT OF PIPERIDYLINDOLE COMPOUND AND PREPARATION METHOD THEREFOR | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2026-03-04 | — | — | EP | disclosed |
| EP-4647121-A3 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| EP-4423076-A4 | PIPERIDINYL INDOLE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | HANSOH BIO LLC (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-4647121-A2 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2025-11-12 | — | — | EP | disclosed |
| EP-4393545-B1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2025-10-08 | — | — | EP | disclosed |
| US-20250243186-A1 | PIPERIDINYL INDOLE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | HANSOH BIO LLC. | 2025-07-31 | — | — | US | disclosed |
| WO-2025148628-A1 | PIPERIDINYL INDOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 河北以岭医药研究院有限公司 | 2025-07-17 | — | — | WO | disclosed |
| US-20250195493-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2025-06-19 | — | — | US | disclosed |
| EP-3675854-B1 | PIPERIDINYL-INDOLE DERIVATIVES FOR USE IN THE TREATMENT OF C3 GLOMERULOPATHY | NOVARTIS AG (CH) | 2025-01-22 | — | — | EP | disclosed |
| WO-2024222852-A1 | SALT OF PIPERIDYLINDOLE COMPOUND AND PREPARATION METHOD THEREFOR | 上海翰森生物医药科技有限公司 | 2024-10-31 | — | — | WO | disclosed |
| EP-4393545-A3 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2024-09-25 | — | — | EP | disclosed |
| EP-4423076-A1 | PIPERIDINYL INDOLE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | Hansoh Bio LLC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118510765-A | Piperidinyl indole derivatives, preparation method and medical application thereof | 翰森生物有限责任公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118510765-A | Piperidinyl indole derivatives, preparation method and medical application thereof | 翰森生物有限责任公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4393545-A2 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | Novartis AG (CH) | 2024-07-03 | — | — | EP | disclosed |
| EP-4126840-A1 | ARYL PIPERIDINES AS MONOACYLGLYCEROL LIPASE MODULATORS | Janssen Pharmaceutica NV (BE) | 2023-02-08 | — | — | EP | disclosed |
| US-20220152011-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | NOVARTIS AG (CH) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250195493-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | C5, C3AR1, FCGRT | HRH3 47/4885BCHE 4599/4885ACHE 4844/4885 |
| US-20220152011-A1 | NOVEL USES OF PIPERIDINYL-INDOLE DERIVATIVES | C5, C3AR1, FCGRT | HRH3 47/4885BCHE 4599/4885ACHE 4844/4885 |
| US-20250243186-A1 | PIPERIDINYL INDOLE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | IDO1, IDO2, TPH1 | HRH3 170/4885BCHE 992/4885ACHE 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.