Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704920 | 1.00 | MAPT (0.51) | MAPTL3MBTL1ABCB1ALDH1A1KMT2A | |
| SCHEMBL9704444 | 0.82 | MAPT (0.56) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9704448 | 0.82 | MAPT (0.56) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9703469 | 0.82 | MAPT (0.48) | MAPTL3MBTL1ABCB1ALDH1A1KMT2A | |
| SCHEMBL9703465 | 0.82 | MAPT (0.48) | MAPTL3MBTL1ABCB1ALDH1A1KMT2A | |
| SCHEMBL9704235 | 0.80 | MAPT (0.53) | MAPTL3MBTL1ALDH1A1KMT2APOLB | |
| SCHEMBL9704228 | 0.80 | MAPT (0.53) | MAPTL3MBTL1ALDH1A1KMT2APOLB | |
| SCHEMBL9703434 | 0.78 | MEN1 (0.56) | MAPTL3MBTL1ALDH1A1KMT2ATSHR | |
| SCHEMBL25355512 | 0.74 | MAPT (0.59) | MAPTL3MBTL1ABCB1ALDH1A1KMT2A | |
| SCHEMBL9365550 | 0.74 | GPR35 (0.56) | MAPTL3MBTL1ALDH1A1KMT2AAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |