Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706025 | 0.80 | L3MBTL1 (0.69) | MEN1HPGDKMT2AL3MBTL1MAPT | |
| SCHEMBL9703477 | 0.80 | MEN1 (0.50) | MEN1HPGDKMT2AL3MBTL1MAPT | |
| SCHEMBL9704149 | 0.80 | HPGD (0.47) | MEN1HPGDKMT2AL3MBTL1MAPT | |
| SCHEMBL16564062 | 0.78 | TSHR (0.58) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL16564059 | 0.78 | TSHR (0.58) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL9704912 | 0.78 | MAPT (0.51) | MEN1KMT2AL3MBTL1MAPTPOLB | |
| SCHEMBL9704920 | 0.78 | MAPT (0.51) | MEN1KMT2AL3MBTL1MAPTPOLB | |
| SCHEMBL30623198 | 0.78 | PKM (0.67) | MEN1HPGDKMT2AL3MBTL1MAPT | |
| SCHEMBL9703402 | 0.78 | PKM (0.67) | MEN1HPGDKMT2AL3MBTL1MAPT | |
| SCHEMBL10631063 | 0.76 | HPGD (0.72) | MEN1HPGDKMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |