Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704444 | 1.00 | MAPT (0.56) | MAPTL3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL9704228 | 0.91 | MAPT (0.53) | MAPTL3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL9704235 | 0.91 | MAPT (0.53) | MAPTL3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL9093727 | 0.88 | L3MBTL1 (0.61) | MAPTL3MBTL1LMNAHTTNPSR1 | |
| SCHEMBL9704920 | 0.82 | MAPT (0.51) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9704912 | 0.82 | MAPT (0.51) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL25355512 | 0.81 | MAPT (0.59) | MAPTL3MBTL1LMNAMAPK1ALDH1A1 | |
| SCHEMBL9704072 | 0.80 | KMT2A (0.48) | MAPTL3MBTL1LMNAMAPK1ALDH1A1 | |
| SCHEMBL9704079 | 0.80 | KMT2A (0.48) | MAPTL3MBTL1LMNAMAPK1ALDH1A1 | |
| SCHEMBL9365284 | 0.79 | PKM (0.59) | MAPTL3MBTL1LMNAHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |