Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.48 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 4/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704267 | 0.79 | ALDH1A1 (0.41) | LMNAHSD17B10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31123058 | 0.78 | DYRK1A (0.58) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL9703952 | 0.76 | GRIN2D (0.60) | GRIN2DGRIN3BGRIK1GRIA1GRIA2 | |
| SCHEMBL9703415 | 0.74 | GRIN2D (0.67) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL9703446 | 0.71 | CDK9 (0.40) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL11349897 | 0.70 | GRIN2D (0.78) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL11349852 | 0.70 | GRIN2D (0.78) | GRIN2DGRIN3BLMNAGRIK1GRIA1 | |
| SCHEMBL16134513 | 0.68 | L3MBTL1 (0.44) | HSD17B10ALDH1A1MAPT | |
| SCHEMBL31620418 | 0.67 | NQO2 (0.36) | — | |
| SCHEMBL16134547 | 0.67 | NQO2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |