Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TYRO3 | Q06418 | 9/20 | 0.38 |
| ▸ | MERTK | Q12866 | 9/20 | 0.38 |
| ▸ | AXL | P30530 | 6/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.38 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.38 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 7/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 7/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705991 | 0.83 | PARP1 (0.47) | PARP1 | |
| SCHEMBL9704936 | 0.79 | POLA1 (0.41) | TYRO3MERTKAXLBCHETRPC3 | |
| SCHEMBL9669702 | 0.78 | PARP1 (0.42) | PARP1TYRO3 | |
| SCHEMBL9704728 | 0.77 | PDE4A (0.43) | TYRO3MERTKAXLFLT3GAS6 | |
| SCHEMBL9705258 | 0.75 | PARP1 (0.40) | PARP1 | |
| SCHEMBL9706003 | 0.75 | PARP1 (0.40) | PARP1 | |
| SCHEMBL7851162 | 0.73 | PARP1 (0.43) | PARP1 | |
| SCHEMBL17099324 | 0.71 | XDH (0.43) | TYRO3MERTKAXLFLT3GAS6 | |
| SCHEMBL29475640 | 0.70 | TYRO3 (0.47) | TYRO3MERTKAXLBCHETRPC3 | |
| SCHEMBL10779046 | 0.70 | XDH (0.44) | TYRO3MERTKAXLFLT3GAS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |