Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 13/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 13/20 | 0.40 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706047 | 0.96 | GP6 (0.40) | AGTR2AGTR1GP6 | |
| SCHEMBL9704951 | 0.92 | GP6 (0.38) | AGTR2AGTR1GP6 | |
| SCHEMBL9034937 | 0.91 | AGTR1 (0.47) | AGTR2AGTR1GP6 | |
| SCHEMBL9733915 | 0.88 | AGTR1 (0.43) | AGTR2AGTR1 | |
| SCHEMBL9035747 | 0.88 | GP6 (0.47) | AGTR2AGTR1GP6 | |
| SCHEMBL9036685 | 0.87 | AGTR2 (0.46) | AGTR2AGTR1GP6 | |
| SCHEMBL9035915 | 0.86 | GP6 (0.47) | AGTR2AGTR1GP6 | |
| SCHEMBL9035407 | 0.86 | AGTR1 (0.49) | AGTR2AGTR1GP6 | |
| SCHEMBL9035158 | 0.85 | GP6 (0.48) | AGTR2AGTR1GP6 | |
| SCHEMBL9734758 | 0.85 | AGTR1 (0.40) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007834-A1 | N-SUBSTITUTED IMIDAZOL-2-ONE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |