Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL965912 | 1.00 | EPHX1 (0.57) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| SCHEMBL1479916 | 1.00 | EPHX1 (0.57) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| Hydrochloric Acid SCHEMBL29096650 | 0.98 | EPHX1 (0.55) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| Water SCHEMBL27340802 | 0.98 | EPHX1 (0.55) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| Hydrochloric Acid SCHEMBL3308273 | 0.98 | EPHX1 (0.55) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| Cyclopropane SCHEMBL27764666 | 0.94 | EPHX1 (0.52) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| SCHEMBL27522920 | 0.94 | PTGS2 (0.62) | EPHX1ALOX5PTGS2LMNAHIF1A | |
| Hypophosphorous Acid SCHEMBL31007070 | 0.92 | EPHX1 (0.50) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| Benzoic Acid SCHEMBL28452765 | 0.90 | TSHR (0.54) | EPHX1ALOX5PTGS2POLBTRPM8 | |
| Trifluoroacetic Acid SCHEMBL6756447 | 0.88 | EPHX1 (0.51) | EPHX1ALOX5PTGS2POLBTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1862 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301736-B1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | LEAD DISCOVERY CENTER GMBH (DE) | 2025-10-08 | — | — | EP | claimed |
| US-12340996-B2 | Method for rapid on-site detection of fentanyl analogs using a miniature mass spectrometer | CHINESE ACADEMY OF INSPECTION AND QUARANTINE (CN) | 2025-06-24 | — | — | US | claimed |
| CN-120155055-A | Composite solution capable of selectively removing carbonyl sulfide in airflow and application thereof | 华东理工大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119505620-A | Hydrogel composite coating and hydrogel composite coating for heat dissipation | 纾酷科技(深圳)有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119193173-A | Dispersing agent and preparation method and application thereof | 蜂巢能源科技股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | QLi5 Therapeutics AG (DE) | 2024-12-19 | — | — | US | claimed |
| CN-118812412-A | Preparation method of spirotrienone and coumarin and derivatives thereof | 黄淮学院 | 2024-10-22 | — | — | CN | claimed |
| CN-117821537-A | Method for synthesizing butyric acid sustained release agent FBA by enzyme method | 江南大学 | 2024-04-05 | — | — | CN | claimed |
| WO-2023218306-A1 | ANTITUMOR ACTIVITY OF MESO-(P-ACETAMIDOPHENYL)-CALIX[4]PYRROLE BY INHIBITION OF THE ENZYMATIC ACTIVITY OF THE PROTEIN GLYCYL-TRNA SYNTHASE 1 (GARS1) | Giam Pharma International sarl (CH) | 2023-11-16 | — | — | WO | claimed |
| CN-116514624-A | N-monofluoromethyl carbonyl compound and preparation method thereof | 中山大学附属第一医院 | 2023-08-01 | — | — | CN | claimed |
| CN-1035847-A | The method for preparing optically active 2-aryl propionic acid | RHONE POULENC SANTE (FR) | 1989-09-27 | — | — | CN | claimed |
| CN-1035846-A | The preparation method of optically active acids of 2-aryl alkane | RHONE POULENC SANTE (FR) | 1989-09-27 | — | — | CN | claimed |
| EP-0330529-A1 | Process for the preparation of optically active 2-aryl-propionic acids | RHONE-POULENC SANTE (FR) | 1989-08-30 | — | — | EP | claimed |
| EP-0326482-A1 | Process for the preparation of optically active 2-aryl-alkanoic acids | RHONE-POULENC SANTE (FR) | 1989-08-02 | — | — | EP | claimed |
| US-RE32944-E | Aromatic carboxylic amide derivatives | Kissei Yakuhin Kogyo Kabushiki (JP) | 1989-06-06 | — | — | US | claimed |
| CN-86105641-A | The method for preparing antianaphylaxis and antibronchospasm of N-dibenzyl-diazacyclo alkyl-alkyl-anilide | — | 1987-04-01 | — | — | CN | claimed |
| EP-0160508-A2 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-06 | — | — | EP | claimed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | claimed |
| US-4070484-A | Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same | KISSEI PHARMACEUTICAL CO., LTD. (JA) | 1978-01-24 | — | — | US | claimed |
| US-3940422-A | ANTIALLERGEN | KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) | 1976-02-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240415819-A1 | MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS | PSMB5, PSMA5, PSMB1 | EPHX1 3367/4885ALOX5 1486/4885PTGS2 3236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.