Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 5/20 | 0.45 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | AOC2 | O75106 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705002 | 1.00 | TRPA1 (0.47) | TRPA1IDO1CTBP2LOXL2TAAR1 | |
| SCHEMBL19632126 | 1.00 | TRPA1 (0.47) | TRPA1IDO1CTBP2LOXL2TAAR1 | |
| SCHEMBL934459 | 0.79 | ESR1 (0.46) | TRPA1IDO1CTBP2TAAR1MIF | |
| SCHEMBL467699 | 0.79 | ESR1 (0.46) | TRPA1IDO1CTBP2TAAR1MIF | |
| SCHEMBL467700 | 0.79 | ESR1 (0.46) | TRPA1IDO1CTBP2TAAR1MIF | |
| SCHEMBL27804585 | 0.78 | TAAR1 (0.45) | TRPA1IDO1CTBP2LOXL2TAAR1 | |
| SCHEMBL31591064 | 0.77 | IDO1 (0.45) | IDO1CTBP2TAAR1AGXT | |
| SCHEMBL5898755 | 0.77 | IDO1 (0.45) | IDO1CTBP2TAAR1MEN1KMT2A | |
| SCHEMBL28533247 | 0.77 | IDO1 (0.45) | IDO1CTBP2TAAR1AGXT | |
| SCHEMBL15117847 | 0.77 | LOXL2 (0.46) | TRPA1IDO1LOXL2TAAR1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230018-B1 | PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-4870100-A | INSECTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| EP-0230018-A2 | Pyrethroide, process for their preparation and their use in combatting parasites as well as precursors for the preparation of these pyrethroids | BASF Aktiengesellschaft (DE) | 1987-07-29 | — | — | EP | disclosed |