SCHEMBL9705002

SCHEMBL9705002

ON=CCc1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.47
IDO1 P14902 5/20 0.45
CTBP2 P56545 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TAAR1 Q96RJ0 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
MIF P14174 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
AGXT P21549 2/20 0.37
MAOA P21397 2/20 0.36
MAOB P27338 2/20 0.36
AOC2 O75106 1/20 0.36
AOC3 Q16853 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9705001 1.00 TRPA1 (0.47) TRPA1IDO1CTBP2LOXL2TAAR1
SCHEMBL19632126 1.00 TRPA1 (0.47) TRPA1IDO1CTBP2LOXL2TAAR1
SCHEMBL934459 0.79 ESR1 (0.46) TRPA1IDO1CTBP2TAAR1MIF
SCHEMBL467699 0.79 ESR1 (0.46) TRPA1IDO1CTBP2TAAR1MIF
SCHEMBL467700 0.79 ESR1 (0.46) TRPA1IDO1CTBP2TAAR1MIF
SCHEMBL27804585 0.78 TAAR1 (0.45) TRPA1IDO1CTBP2LOXL2TAAR1
SCHEMBL31591064 0.77 IDO1 (0.45) IDO1CTBP2TAAR1AGXT
SCHEMBL5898755 0.77 IDO1 (0.45) IDO1CTBP2TAAR1MEN1KMT2A
SCHEMBL28533247 0.77 IDO1 (0.45) IDO1CTBP2TAAR1AGXT
SCHEMBL15117847 0.77 LOXL2 (0.46) TRPA1IDO1LOXL2TAAR1MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101215246-B Method for preparing alpha-ketoxime acid ester UNIV HEBEI SCIENCE & TECH 2010-08-18 CN claimed
CN-101215246-A Method for preparing alpha-ketoxime acid ester UNIV HEBEI SCIENCE & TECH (CN) 2008-07-09 CN claimed
CN-110078746-B 2-carbonyl thiazolothiophene compound with luminescent property and preparation method and application thereof 华南理工大学 2022-03-25 CN disclosed
CN-108355709-B Application of bismuth trifluoromethanesulfonate as Beckmann rearrangement reaction catalyst 嘉兴学院 2020-12-08 CN disclosed
EP-0230018-B1 PYRETHROIDE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN COMBATTING PARASITES AS WELL AS PRECURSORS FOR THE PREPARATION OF THESE PYRETHROIDS BASF Aktiengesellschaft (DE) 1992-08-26 EP disclosed
US-4870100-A INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed
EP-0230018-A2 Pyrethroide, process for their preparation and their use in combatting parasites as well as precursors for the preparation of these pyrethroids BASF Aktiengesellschaft (DE) 1987-07-29 EP disclosed