Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705657 | 0.80 | GLP1R (0.47) | GLP1RKDM5BMAPTKDM4EALDH1A1 | |
| SCHEMBL9704126 | 0.80 | POLB (0.45) | KDM5BPOLBMAPTKDM4EALDH1A1 | |
| SCHEMBL6377225 | 0.77 | SIRT2 (0.56) | ALDH1A1SIRT2SIRT1SIRT3ALOX15 | |
| SCHEMBL9703575 | 0.76 | GRIN2D (0.63) | GLP1RSIRT2SIRT1SIRT3HTT | |
| SCHEMBL11372297 | 0.75 | ALDH1A1 (0.46) | POLBMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9704059 | 0.74 | ADORA3 (0.55) | GLP1RALDH1A1HPGDSIRT2SIRT1 | |
| SCHEMBL2779501 | 0.74 | MAP3K5 (0.46) | POLBMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30623229 | 0.74 | ADORA3 (0.55) | GLP1RALDH1A1HPGDSIRT2SIRT1 | |
| SCHEMBL11366574 | 0.74 | GLP1R (0.42) | GLP1RPOLBMAPTALDH1A1NPC1 | |
| SCHEMBL6377630 | 0.74 | ALDH1A1 (0.51) | POLBKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |