Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704414 | 0.84 | DHODH (0.55) | DHODHCTRCHSD11B1PSMB5ADORA1 | |
| SCHEMBL24755295 | 0.82 | HSD11B1 (0.59) | DHODHCTRCHSD11B1PSMB5ADORA1 | |
| SCHEMBL12369304 | 0.81 | ASIC3 (0.47) | DHODHHSD11B1PSMB5GPR84KMT2A | |
| SCHEMBL9704527 | 0.80 | SMN1; SMN2 (0.51) | ADORA1CTSKADORA3ADORA2AMEN1 | |
| SCHEMBL16383499 | 0.79 | DHODH (0.51) | DHODHCTRCHSD11B1PSMB5MEN1 | |
| SCHEMBL27407916 | 0.79 | HSD11B1 (0.50) | HSD11B1PSMB5GPR84RAB9A | |
| SCHEMBL11513697 | 0.79 | HSD11B1 (0.50) | HSD11B1PSMB5GPR84RAB9A | |
| SCHEMBL12628232 | 0.77 | HSD11B1 (0.56) | DHODHCTRCHSD11B1ADORA1ADORA3 | |
| SCHEMBL27917367 | 0.76 | DHODH (0.58) | DHODHADORA1TLR8ADORA3 | |
| SCHEMBL12551317 | 0.76 | MEN1 (0.54) | ADORA1ADORA2AMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | claimed |
| EP-0463492-A1 | 2,6-Diarylpyridin derivatives | BAYER AG (DE) | 1992-01-02 | — | — | EP | disclosed |