Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641321 | 0.86 | TDP1 (0.49) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL32667982 | 0.81 | ALOX15 (0.45) | TDP1ALOX15TSHRKDM4EFDPS | |
| Pentetic Acid SCHEMBL10361749 | 0.78 | TDP1 (0.60) | TDP1ALOX15TSHRCYP2C19KDM4E | |
| SCHEMBL4296152 | 0.78 | AKR1B1 (0.61) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL11152664 | 0.77 | TSHR (0.53) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL22916771 | 0.77 | AKR1B1 (0.59) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL18161886 | 0.77 | KEAP1 (0.43) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL8930119 | 0.76 | TDP1 (0.49) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL20494540 | 0.76 | NPC1 (0.46) | KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL72851 | 0.75 | AKR1B1 (0.61) | TDP1TSHRCYP2C19KDM4EFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013965-A1 | METHOD OF IMMOBILIZING AND CROSSLINKING PROTEINS AND OTHER MOLECULES AND USES THEREOF | ANDERSON LESLIE DERIEMER (US) | 1992-08-20 | — | — | WO | disclosed |
| WO-1989006980-A1 | RADIOPHARMACEUTICALS | UNIVERSITY OF QUEENSLAND (AU) | 1989-08-10 | — | — | WO | disclosed |
| WO-1989006980-A1 | RADIOPHARMACEUTICALS | UNIVERSITY OF QUEENSLAND (AU) | 1989-08-10 | — | — | WO | disclosed |