Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18161901 | 0.92 | ALOX15 (0.41) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL641321 | 0.90 | TDP1 (0.49) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL4296152 | 0.78 | AKR1B1 (0.61) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL11152664 | 0.77 | TSHR (0.53) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL22916771 | 0.77 | AKR1B1 (0.59) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL9705112 | 0.77 | TDP1 (0.42) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL8930119 | 0.76 | TDP1 (0.49) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL22826566 | 0.75 | MAPT (0.67) | KEAP1CYSLTR2CYSLTR1MAPTRXFP1 | |
| SCHEMBL3689872 | 0.75 | AKR1B1 (0.52) | KEAP1TDP1ALOX15TSHRCYP2C19 | |
| SCHEMBL847204 | 0.74 | TDP1 (0.44) | KEAP1TDP1ALOX15TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304473-A1 | EXCIMER FORMING COMPOUNDS | PHAX, RNMT, POLM | KEAP1 4789/4885TDP1 1179/4885ALOX15 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.