Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 17/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705213 | 1.00 | HTR3A (0.52) | HTR3A | |
| SCHEMBL9705203 | 0.83 | HTR3A (0.53) | HTR3A | |
| SCHEMBL10388774 | 0.80 | HTR3A (0.67) | HTR3A | |
| SCHEMBL8320837 | 0.80 | ALDH1A1 (0.69) | HTR3A | |
| SCHEMBL8319139 | 0.80 | ALDH1A1 (0.69) | HTR3A | |
| SCHEMBL8319138 | 0.80 | ALDH1A1 (0.69) | HTR3A | |
| Hydrochloric Acid SCHEMBL10389213 | 0.79 | HTR3A (0.66) | HTR3A | |
| SCHEMBL8323478 | 0.77 | ALDH1A1 (0.66) | HTR3A | |
| SCHEMBL8323170 | 0.77 | KCNH2 (0.68) | HTR3A | |
| SCHEMBL8323177 | 0.77 | KCNH2 (0.68) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518767-A2 | Derivatives of amide analogs of certain methano bridged quinolizines | MERRELL PHARMACEUTICALS INC. (US) | 1992-12-16 | — | — | EP | claimed |