Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.45 |
| ▸ | NOS2 | P35228 | 5/20 | 0.45 |
| ▸ | NOS3 | P29474 | 4/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27573343 | 0.96 | PI4KA (0.45) | NOS1NOS2NOS3PI4KAPI4K2B | |
| SCHEMBL18786068 | 0.94 | PI4KA (0.44) | NOS1NOS2NOS3PI4KAPI4K2B | |
| SCHEMBL9706008 | 0.88 | NOS3 (0.40) | NOS1NOS2NOS3PI4KAPI4K2B | |
| SCHEMBL9705258 | 0.77 | PARP1 (0.40) | NOS1NOS2NOS3PI4KAPI4K2B | |
| SCHEMBL7175004 | 0.77 | TP53 (0.32) | NOS1NOS2NOS3ALDH1A1 | |
| SCHEMBL9704936 | 0.74 | POLA1 (0.41) | NOS1NOS2NOS3PI4KAPI4K2B | |
| SCHEMBL7851163 | 0.74 | PI4KA (0.49) | NOS1NOS2NOS3PI4KAPI4K2B | |
| SCHEMBL18757838 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1 | |
| SCHEMBL24520486 | 0.72 | CYP1A2 (0.32) | CYP2C9 | |
| SCHEMBL7071670 | 0.70 | PDK2 (0.44) | NOS1NOS2NOS3PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |