SCHEMBL7071670

SCHEMBL7071670

CCCc1nc2nc(C)ncc2[nH]1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.44
PDK4 Q16654 2/20 0.42
ADORA3 P0DMS8 2/20 0.36
ADORA2A P29274 2/20 0.36
ADORA1 P30542 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PI4KA P42356 1/20 0.35
PI4K2B Q8TCG2 1/20 0.35
PI4K2A Q9BTU6 1/20 0.35
PI4KB Q9UBF8 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
POLB P06746 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14743780 0.81 ALDH1A1 (0.43) ADORA3ADORA2AADORA1KMT2AKDM4E
SCHEMBL27681615 0.78 KDM4E (0.41) PDK2ADORA3ADORA2AADORA1KDM4E
SCHEMBL7618865 0.75 SMN1; SMN2 (0.50) PDK2PDK4ADORA3ADORA2AADORA1
SCHEMBL7071667 0.72 PDK2 (0.51) PDK2PDK4KMT2AKDM4EKDM4C
SCHEMBL7068568 0.71 SMN1; SMN2 (0.42) PDK2PDK4ADORA2AADORA1
SCHEMBL1551964 0.71 PDK2 (0.36) PDK2PDK4KDM4E
SCHEMBL17515056 0.71 SMN1; SMN2 (0.34) PDK2
SCHEMBL1551605 0.71 NUDT1 (0.44) KMT2AKDM4ENOS1
SCHEMBL9705260 0.70 NOS1 (0.45) PI4KAPI4K2BPI4K2API4KBNOS3
SCHEMBL9706008 0.70 NOS3 (0.40) PI4KAPI4K2BPI4K2API4KBNOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-3265447-B1 BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-03-01 EP disclosed
CN-107428708-B Benzoxazine low temperature curable compositions 亨斯迈先进材料美国有限责任公司 2021-11-09 CN disclosed
US-20180030264-A1 Benzoxazine Low Temperature Curable Composition HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2018-02-01 US disclosed
EP-3265447-A1 BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION Huntsman Advanced Materials Americas LLC (US) 2018-01-10 EP disclosed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030264-A1 Benzoxazine Low Temperature Curable Composition CRYZ, PIEZO1, PSMD12 PDK2 2639/4885PDK4 2411/4885ADORA3 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.