Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10422734 | 0.79 | REN (0.32) | BACE1RENADORA3ADORA2AADORA2B | |
| SCHEMBL9705305 | 0.78 | GRIN2B (0.34) | — | |
| SCHEMBL5567101 | 0.76 | CTSL (0.36) | RENCTSLITGB3ITGA2BCTSB | |
| SCHEMBL21724565 | 0.73 | BACE1 (0.51) | BACE1RENCTSLCTSBCTSS | |
| SCHEMBL9980636 | 0.73 | BACE1 (0.51) | BACE1RENCTSLCTSBCTSS | |
| SCHEMBL21724562 | 0.73 | BACE1 (0.51) | BACE1RENCTSLCTSBCTSS | |
| SCHEMBL21724228 | 0.73 | BACE1 (0.51) | BACE1RENCTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL21724538 | 0.72 | BACE1 (0.50) | BACE1RENCTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL21724540 | 0.72 | BACE1 (0.50) | BACE1RENCTSLCTSBCTSS | |
| SCHEMBL21737915 | 0.71 | BACE1 (0.48) | BACE1RENCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209643-B1 | PEPTIDE COMPOSITION USEFUL FOR THE MALARIA VACCINE MANUFACTURE AS WELL AS FOR THE PREPARATION OF DIAGNOSTIC KITS FOR THE DETECTION OF MALARIAL DISEASES | ENIRICERCHE S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |
| US-4956449-A | Forming polypeptides from tetrapeptides condensed and separated by chromatography | ENIRICERCHE, S.P.A. (IT) | 1990-09-11 | — | — | US | disclosed |