SCHEMBL9705305

SCHEMBL9705305

CC(C)(C)OC(=O)C1(C(=O)O)CCCN1C(=O)C(N)CC(N)=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
ARG1 P05089 1/20 0.31
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10422734 0.83 REN (0.32) GRIN2BGRIN2C
SCHEMBL9705363 0.80 MAPT (0.32) DPP4
SCHEMBL28779766 0.79 GRIN2B (0.36) GRIN2BGRIN2C
SCHEMBL9705287 0.78 BACE1 (0.39)
SCHEMBL9518563 0.73 CYP4F2 (0.32) GRIN2BGRIN2C
SCHEMBL630080 0.72 GRIN2B (0.38) GRIN2BGRIN2C
SCHEMBL8585741 0.70 HPGD (0.33)
SCHEMBL7382306 0.70 CYP4F2 (0.33)
SCHEMBL2216266 0.70 HPGD (0.33)
SCHEMBL1963765 0.69 GRIN2B (0.32) GRIN2BGRIN2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0209643-B1 PEPTIDE COMPOSITION USEFUL FOR THE MALARIA VACCINE MANUFACTURE AS WELL AS FOR THE PREPARATION OF DIAGNOSTIC KITS FOR THE DETECTION OF MALARIAL DISEASES ENIRICERCHE S.p.A. (IT) 1992-07-08 EP disclosed
US-4956449-A Forming polypeptides from tetrapeptides condensed and separated by chromatography ENIRICERCHE, S.P.A. (IT) 1990-09-11 US disclosed
EP-0209643-A2 Peptide composition useful for the malaria vaccine manufacture as well as for the preparation of diagnostic kits for the detection of malarial diseases ENIRICERCHE S.p.A. (IT) 1987-01-28 EP disclosed