Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278091 | 0.78 | HCAR2 (0.39) | TSHRTP53EGLN1EGLN3GABRR1 | |
| SCHEMBL28831593 | 0.78 | HCAR2 (0.39) | TSHRTP53EGLN1EGLN3GABRR1 | |
| SCHEMBL3278419 | 0.75 | HCAR2 (0.42) | ALDH1A1 | |
| SCHEMBL3971339 | 0.74 | MAPT (0.39) | — | |
| Trolamine SCHEMBL6479985 | 0.74 | TSHR (0.50) | TSHRTP53EGLN1EGLN3NPC1 | |
| Trolamine SCHEMBL4944913 | 0.74 | TSHR (0.50) | TSHRTP53EGLN1EGLN3NPC1 | |
| Trolamine SCHEMBL5875419 | 0.74 | TSHR (0.50) | TSHRTP53EGLN1EGLN3NPC1 | |
| Trolamine SCHEMBL14989224 | 0.74 | TSHR (0.50) | TSHRTP53EGLN1EGLN3NPC1 | |
| Trolamine SCHEMBL4944905 | 0.74 | TSHR (0.50) | TSHRTP53EGLN1EGLN3NPC1 | |
| Trolamine SCHEMBL5874734 | 0.74 | TSHR (0.50) | TSHRTP53EGLN1EGLN3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226153-B1 | IONIC POLYMERS | BASF Aktiengesellschaft (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0226153-A2 | Ionic polymers | BASF Aktiengesellschaft (DE) | 1987-06-24 | — | — | EP | disclosed |