Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.32 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706174 | 0.85 | CNR1 (0.35) | POLBGPR119EPHX2BACE1CTSD | |
| SCHEMBL9705697 | 0.78 | GRIN2B (0.34) | POLBGPR119MEN1KMT2A | |
| SCHEMBL7280493 | 0.76 | EPHX1 (0.33) | MEN1KMT2ABACE1CTSDRABGGTB | |
| SCHEMBL7284224 | 0.76 | EPHX1 (0.33) | MEN1KMT2ABACE1CTSDRABGGTB | |
| SCHEMBL9183699 | 0.76 | EPHX1 (0.33) | MEN1KMT2ABACE1CTSDRABGGTB | |
| SCHEMBL9438077 | 0.76 | RABGGTB (0.34) | GPR119MEN1KMT2ABACE1CTSD | |
| SCHEMBL9845923 | 0.76 | GPR119 (0.37) | GPR119MEN1KMT2ARABGGTBRABGGTA | |
| SCHEMBL9841957 | 0.75 | SMN1; SMN2 (0.35) | MEN1KMT2ABACE1CTSDRABGGTB | |
| SCHEMBL7286513 | 0.75 | SMN1; SMN2 (0.35) | MEN1KMT2ABACE1CTSDRABGGTB | |
| SCHEMBL7378315 | 0.75 | SMN1; SMN2 (0.41) | GPR119MEN1KMT2AFAAHRABGGTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4266877-A | — | — | None | — | — | JP | disclosed |
| JP-H04266877-A | AMINODIOL DERIVATIVE | HOECHST AG | 1992-09-22 | — | — | JP | disclosed |
| EP-0487980-A1 | Aminodiols-derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-03 | — | — | EP | disclosed |