Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.33 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9438059 | 0.91 | GPR119 (0.36) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL7378315 | 0.84 | SMN1; SMN2 (0.41) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL7378313 | 0.84 | SMN1; SMN2 (0.41) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL7292645 | 0.83 | HPGD (0.41) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL9444930 | 0.83 | HPGD (0.41) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL9438091 | 0.83 | REN (0.38) | GPR119MEN1KMT2AHPGDRABGGTB | |
| SCHEMBL7377791 | 0.83 | SMN1; SMN2 (0.40) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL7377787 | 0.83 | SMN1; SMN2 (0.40) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL7373639 | 0.82 | GPR119 (0.34) | GPR119MEN1KMT2AHPGDRECQL | |
| SCHEMBL7369146 | 0.82 | BMP1 (0.36) | GPR119MEN1KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456039-A2 | Renin inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1991-11-13 | — | — | EP | disclosed |