Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MARK3 | P27448 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390058 | 1.00 | PDPK1 (0.36) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL6747378 | 0.79 | XDH (0.37) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL20793714 | 0.79 | PDPK1 (0.36) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL1675432 | 0.79 | NOS1 (0.39) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL4523840 | 0.78 | PDE4A (0.41) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL19777975 | 0.77 | PDPK1 (0.35) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL19778471 | 0.76 | LRRK2 (0.34) | PDPK1CHEK1AURKACHEK2HSP90AA1 | |
| SCHEMBL9925954 | 0.76 | PDPK1 (0.34) | PDPK1PRKACA | |
| SCHEMBL2526551 | 0.75 | PARP1 (0.32) | PDPK1 | |
| SCHEMBL128574 | 0.73 | PDPK1 (0.39) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339916-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-10-26 | — | — | US | disclosed |
| EP-4208458-A1 | PLANT GROWTH REGULATOR COMPOUNDS | Syngenta Crop Protection AG (CH) | 2023-07-12 | — | — | EP | disclosed |
| US-9775841-B2 | Compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2017-10-03 | — | — | US | disclosed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339916-A1 | PLANT GROWTH REGULATOR COMPOUNDS | MYB, TOE1, SUB1 | PDPK1 1146/4885CHEK1 4085/4885AURKA 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.