Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9705714 | 0.98 | TTR (0.45) | TTRTSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL9862894 | 0.85 | NISCH (0.41) | CYP2C9CYP1A2CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL9666810 | 0.81 | ESR2 (0.44) | TSHRHSD17B10LSS | |
| SCHEMBL3794785 | 0.80 | KCNH2 (0.38) | LSSSMN1; SMN2KCNH2HRH3 | |
| SCHEMBL7519297 | 0.79 | KCNH2 (0.34) | LSSSMN1; SMN2KCNH2HRH3 | |
| SCHEMBL6670692 | 0.79 | KCNH2 (0.34) | LSSKCNH2HRH3 | |
| SCHEMBL9700423 | 0.78 | CA1 (0.46) | ALDH1A1CYP2C9CYP1A2CYP2C19KCNH2 | |
| SCHEMBL29367971 | 0.78 | AHR (0.46) | TSHRHSD17B10ALDH1A1LSSALOX15 | |
| Hydrochloric Acid SCHEMBL9705801 | 0.76 | CRHBP (0.37) | TTRTSHRHSD17B10ALDH1A1CYP3A4 | |
| SCHEMBL7303946 | 0.76 | LSS (0.33) | LSSSMN1; SMN2KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4861791-A | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents | STERLING DRUG INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |