Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CFB | P00751 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668282 | 0.81 | HSD17B1 (0.41) | CYP2C19SCARB1 | |
| SCHEMBL3794785 | 0.80 | KCNH2 (0.38) | MMP13KCNH2HRH3ADRA2ALTA4H | |
| SCHEMBL6670692 | 0.79 | KCNH2 (0.34) | MMP13KCNH2HRH3LTA4H | |
| SCHEMBL7519297 | 0.79 | KCNH2 (0.34) | MMP13KCNH2HRH3ADRA2AADRA1A | |
| SCHEMBL9705736 | 0.78 | TTR (0.46) | CYP1A2CYP2C9CYP2C19KCNH2HRH3 | |
| SCHEMBL9862946 | 0.77 | CA2 (0.52) | CA1CA2CYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL9705714 | 0.76 | TTR (0.45) | CYP1A2CYP2C9CYP2C19KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL9705801 | 0.76 | CRHBP (0.37) | KCNH2HRH3ALDH1A1LTA4H | |
| SCHEMBL7832996 | 0.74 | SCARB1 (0.37) | SCARB1KCNH2HRH3ALDH1A1LMNA | |
| SCHEMBL9862894 | 0.72 | NISCH (0.41) | CA1CA2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5128422-A | Molding materials | HUELS AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| EP-0468162-A1 | Modified polyphenylene ether based thermoplastic moulding compositions | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-5039746-A | Solvent resistant; engineering thermoplastics | HUELS AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |
| US-5039781-A | Polyphenylene ether end capped with oxazoline moiety | HUELS AKTIENGESELLSCHAFT (DE) | 1991-08-13 | — | — | US | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0391031-A2 | Block copolymers based on polyphenylene ethers and polycondensates, and a process for their preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1990-10-10 | — | — | EP | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0338208-A1 | Functionalized polyphenylene ether and method for its preparation | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338209-A2 | Thermoplastic molding masses on the basis of functionalized polyphenylenethers and polyamides | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-10-25 | — | — | EP | disclosed |
| US-4861791-A | Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents | STERLING DRUG INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |