Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 2/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9668165 | 0.83 | HPGD (0.51) | TAS1R3TAS1R1HPGDGAAALDH1A1 | |
| SCHEMBL14627779 | 0.82 | GRN (0.61) | TAS1R3TAS1R1HPGDGAAALDH1A1 | |
| SCHEMBL13754417 | 0.82 | GRN (0.61) | TAS1R3TAS1R1HPGDGAAALDH1A1 | |
| SCHEMBL15631141 | 0.75 | ACLY (0.48) | TAS1R3TAS1R1GAAALDH1A1TTR | |
| SCHEMBL13970564 | 0.74 | GRN (0.43) | TAS1R3TAS1R1HPGDGAAALDH1A1 | |
| SCHEMBL13753580 | 0.74 | HPGD (0.72) | HPGDALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL13021056 | 0.74 | CA2 (0.44) | GAATTRNPC1KMT2AMEN1 | |
| SCHEMBL17732590 | 0.73 | ACLY (0.47) | TAS1R3TAS1R1GAAALDH1A1TTR | |
| SCHEMBL9705735 | 0.73 | HPGD (0.54) | HPGDGAAALDH1A1TTRNPC1 | |
| SCHEMBL9863174 | 0.73 | BRD4 (0.46) | GAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0207454-A2 | Isoxazole and furan derivatives, their preparation and use as antiviral agents | STERLING WINTHROP INC. (US) | 1987-01-07 | — | — | EP | disclosed |