Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878978 | 0.78 | KDM4E (0.63) | HPGDKDM4EACSS2GAAKMT2A | |
| SCHEMBL13018868 | 0.76 | POLB (0.53) | HPGDNPC1KDM4ETTRGAA | |
| SCHEMBL19836092 | 0.76 | MEN1 (0.58) | HPGDNPC1KDM4EKMT2ARAB9A | |
| SCHEMBL19835585 | 0.76 | MEN1 (0.58) | HPGDNPC1KDM4EKMT2ARAB9A | |
| SCHEMBL15087817 | 0.76 | MEN1 (0.58) | HPGDNPC1KDM4EKMT2ARAB9A | |
| SCHEMBL9705706 | 0.74 | HPGD (0.67) | HPGDNPC1KDM4ETTRGAA | |
| SCHEMBL9668334 | 0.74 | MPO (0.52) | HPGDNPC1ACSS2GAAKMT2A | |
| SCHEMBL9717443 | 0.74 | GAA (0.77) | HPGDNPC1KDM4EACSS2GAA | |
| SCHEMBL9705789 | 0.73 | TAS1R3 (0.45) | HPGDNPC1TTRGAAKMT2A | |
| SCHEMBL30732620 | 0.73 | ABCB1 (0.46) | HPGDNPC1KDM4ETTRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207454-B1 | ISOXAZOLE AND FURAN DERIVATIVES, THEIR PREPARATION AND USE AS ANTIVIRAL AGENTS | STERLING WINTHROP INC. (US) | 1992-09-09 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |