Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | PGR | P06401 | 2/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705867 | 1.00 | SHBG (0.66) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL3029696 | 0.87 | LMNA (0.67) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL11660767 | 0.86 | SHBG (0.61) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL11660763 | 0.86 | SHBG (0.61) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL10745748 | 0.85 | SHBG (0.49) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL10745742 | 0.85 | SHBG (0.49) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL11440167 | 0.85 | SHBG (0.60) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL11427618 | 0.85 | SHBG (0.60) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL11427622 | 0.85 | SHBG (0.60) | SHBGNR3C1ALDH1A1PGRADRA1A | |
| SCHEMBL9643566 | 0.84 | SHBG (0.48) | SHBGNR3C1ALDH1A1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218647-B1 | SKIN TREATMENT AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-06-17 | — | — | EP | disclosed |
| US-4859659-A | ACNE TREATMENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| US-4673673-A | ANTIANDROGENS | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-06-16 | — | — | US | disclosed |
| EP-0062903-A1 | 17-Alpha-alkyl-17-beta-hydroxy-1-alpha-methyl-4-androsten-3-ones, process for their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-10-20 | — | — | EP | disclosed |