Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | SHBG | P04278 | 6/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777671 | 0.89 | LMNA (0.67) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL3777666 | 0.89 | LMNA (0.67) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL10425177 | 0.88 | HSD17B10 (0.69) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL28750427 | 0.88 | LMNA (0.66) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL9705874 | 0.87 | SHBG (0.66) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL9705867 | 0.87 | SHBG (0.66) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL571164 | 0.85 | LMNA (0.62) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL8415805 | 0.83 | NR3C1 (0.56) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL8415802 | 0.83 | NR3C1 (0.56) | LMNASHBGCYP2C19NR3C1SERPINA6 | |
| SCHEMBL9643566 | 0.82 | SHBG (0.48) | LMNASHBGCYP2C19NR3C1SERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236791-B2 | Assays for S100 inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-08-07 | — | — | US | disclosed |
| US-20100216776-A1 | Assays for S100 inhibitors | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2010-08-26 | — | — | US | disclosed |
| WO-2008094410-A9 | PARALLEL PROFILING OF SIGNALING PATHWAYS | EINSTEIN COLL MED (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008094410-A2 | PARALLEL PROFILING OF SIGNALING PATHWAYS | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008054354-A2 | ASSAYS FOR S1OO INHIBITORS | ALBERT EINSTEIN COLLEGE OF MEDECINE OF YESHIVA UNIVERSITY (US) | 2008-05-08 | — | — | WO | disclosed |