Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706283 | 0.89 | MAPT (0.49) | POLBHDAC1HDAC8HDAC6PTGER4 | |
| Dimethylamine SCHEMBL9706082 | 0.80 | NLRP3 (0.54) | TP53MAPTHPGDHTTKDM4E | |
| SCHEMBL6655074 | 0.79 | PTGER4 (0.45) | POLBHDAC1HDAC8HDAC6PTGER4 | |
| SCHEMBL9706138 | 0.78 | KDM4E (0.46) | POLBHDAC1HDAC8HDAC6PTGER4 | |
| Hydrochloric Acid SCHEMBL8025753 | 0.78 | HPGD (0.63) | POLBHDAC1HDAC8HDAC6TP53 | |
| SCHEMBL15139648 | 0.74 | PKM (0.70) | POLBTP53TOP2AHPGDPKM | |
| SCHEMBL9706071 | 0.74 | LMNA (0.42) | POLBTP53MAPTHPGDKDM4E | |
| SCHEMBL6400968 | 0.73 | HTT (0.76) | POLBTP53MAPTHTTKDM4E | |
| Hydrochloric Acid SCHEMBL7176360 | 0.73 | POLB (0.51) | POLBHDAC1HDAC8HDAC6TP53 | |
| Hydrochloric Acid SCHEMBL7181491 | 0.73 | POLB (0.51) | POLBHDAC1HDAC8HDAC6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |