Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706123 | 0.90 | MAPT (0.47) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL9706158 | 0.89 | MAPT (0.60) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL9706140 | 0.88 | MAPT (0.66) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL1581069 | 0.83 | MAPT (0.71) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL9436917 | 0.81 | KDM4E (0.54) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL9706088 | 0.80 | MAPK1 (0.50) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL9706117 | 0.77 | MAPK1 (0.47) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| SCHEMBL9706257 | 0.76 | ALOX15 (0.80) | MAPTL3MBTL1KDM4EMAPK1HPGD | |
| Dimethylamine SCHEMBL9706176 | 0.76 | MAPT (0.67) | MAPTL3MBTL1KDM4ETDP1MAPK1 | |
| Dimethylamine SCHEMBL9706312 | 0.74 | MAPT (0.71) | MAPTL3MBTL1KDM4ETDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | claimed |
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |