Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.65 |
| ▸ | CASP7 | P55210 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412926 | 0.84 | CYP1A2 (0.61) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL24108671 | 0.84 | CYP1A2 (0.61) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL9706192 | 0.84 | MAPT (0.47) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL8832028 | 0.81 | NPC1 (0.65) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL29572859 | 0.79 | RAB9A (1.00) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL278729 | 0.79 | RAB9A (1.00) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL8689444 | 0.78 | PTGES (0.49) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL8113168 | 0.77 | SMN1; SMN2 (0.59) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL9706196 | 0.76 | CYP1A2 (0.71) | CASP1CASP7RAB9ATP53NPC1 | |
| SCHEMBL278691 | 0.75 | NPC1 (0.72) | CASP1CASP7RAB9ATP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238459-B1 | SUBSTITUTED INDOLOQUINOXALINES | Lundblad, Leif (SE) | 1992-04-15 | — | — | EP | disclosed |
| US-4990510-A | Viricides, anticancer agents | LEIF LUNDBLAD (BE) | 1991-02-05 | — | — | US | disclosed |
| EP-0238459-A1 | Substituted indoloquinoxalines | Lundblad, Leif (SE) | 1987-09-23 | — | — | EP | disclosed |
| WO-1987004436-A1 | SUBSTITUTED INDOLOQUINOXALINES | LUNDBLAD, LEIF (SE) | 1987-07-30 | — | — | WO | disclosed |